Antibody-directed T cell targeting
Conjugating antibodies to the LNP surface to steer particles onto T cells, generating CAR-T inside the patient rather than in a manufacturing suite.
Research interests
Most of an intravenous LNP dose goes to the liver whether you want it to or not. Three stages of work on that — and on what it makes treatable.
How do you make the particle choose where it goes?
Conjugating antibodies to the LNP surface to steer particles onto T cells, generating CAR-T inside the patient rather than in a manufacturing suite.
Screening pharmacologically active small molecules as a fifth lipid component, so the additive carries its own pharmacology while also shifting expression and biodistribution.
LNP–RNA work assistant
Practical tools for formulation design, experimental planning, measurement, and traceable LNP–RNA records.
Formulation · Screening · RiboGreen
Design lipid formulations, compare screening batches, and calculate RNA concentration and encapsulation efficiency.
02Design · Conjugation · Purification · In vitro / in vivo
Record the complete targeted-LNP workflow, from formulation and conjugation to purification and biological studies.
03IVT batches · RNA library · Experimental records
Track IVT batches and maintain a searchable mRNA library for downstream LNP studies.